Nathan MacKinnon will play Friday when the Avalanche and Rangers meet at the Pepsi Center.
Rangers coach Alain Vigneault said forward Rick Nash won't play after injuring his back in practice Thursday. Emerson Etem will replace him in the lineup.
Here are the game notes.
MacKinnon injured his right hand and/or thumb with less than a minute to play in the Avalanche's 4-2 loss in Arizona on Thursday. He was skating down left wing along the boards when he took a hit from Coyotes defenseman Zbynek Michalek and went to the bench in obvious pain.
The Avalanche didn't have a morning skate Friday, but MacKinnon looked fine in the warmup while shooting pucks with force. He leads the team in scoring with 14 points (five goals, nine assists).
The Avalanche will hit the road for seven games after Friday. The next home game is Nov. 25 against Ottawa.
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Reto Berra will start in goal for the Avalanche, Henrik Lundqvist for the Rangers. It will be Lundqvist's 742nd career game (regular season and playoffs), tying him with Mike Richter for the most in franchise history.
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The Avalanche didn't play with much urgency Thursday until they fell behind 3-1, a disturbing trend. Roy shuffled the lines (again), putting Carl Soderberg between Gabriel Landeskog and Jarome Iginla, and MacKinnon between Alex Tanguay and Matt Duchene.
The Avalanche closed to 3-2 when MacKinnon fed Duchene cutting to the net with 3:46 left in regulation, but the Coyotes clinched matters on Jordan Martinook's empty-net goal with 14 seconds to play. Coyotes goalie Mike Smith gave up eight goals on 30 shots in a little over three periods in his previous two games.
Arizona defenseman Nicklas Grossman, who now has 12 goals in 543 NHL games, scored twice.
Three players, two from the Avalanche, were standing in front of goalie Semyon Varlamov when Grossman scored at 7:05 of the first period. Tobias Rieder made it 2-0 at 2:41 of the second period with a shot that hit Landeskog and bounced between Varlamov's pads after an awful turnover by Nikita Zadorov, who was minus-3.
Cody McLeod put in a rebound at 3:48 to make it 2-1 following an end-to-end rush by Erik Johnson, but Grossman was credited with his second goal at 5:16. Varlamov stopped his original shot but when he tried to push the puck away rather than cover it, it ricocheted off Avalanche center Ben Street, who crashed into the net with Arizona's Steve Downie.
Roy used his coach's challenge, believing Downie pushed Street into Varlamov, but the goal was allowed to stand.